Obesity and breast cancer — Association even more relevant in males?

PUBLISH – European Journal of Internal Medicine 29 (2016) e11–e12

Authors :  Djordje S. Popovic, Clinic for Endocrinology, Diabetes and Metabolic Disorders, Clinical Centerof Vojvodina, Medical Faculty, University of Novi Sad, Serbia

Lazar S. Popovic, Clinic for Medical Oncology, Institute for Oncology of Vojvodina, Sremska Kamenica, Medical Faculty, University of Novi Sad, Serbia

Keywords: Male breast cancer, Male gender, Obesity, Adipose tissue

Male breast cancer (MBC) is a rare disease. It accounts for a less than 1% of total malignant diseases and for a less than 1% of all breast cancer cases. Besides the fact that it is much less frequent than a female breast cancer (FBC), MBC is a disease that deserves a full attention of the whole society. Although global incidence of MBC of around 8000 cases is still relatively low, the rise in the incidence from 0.86 to 1.08 per 100000 in twenty five year period (from 1973 to 1998) and the increment in the lifetime risk of getting Male breast cancer to 1 in 1000  in the United States of America, should raise the awareness of MBC among all health care professionals. MBC typically presents in the seventh decade, approximately five years later than FBC. Males are more likely to have estrogen/progesterone positive tumors and poorer prognosis in comparison to females. Regarding the racial distribution, Male breast cancer, is more frequent among black men. For the record, analysis conducted among patients treated at our regional reference institution also shows that MBC is diagnosed at more advanced stages of disease and that it has poorer prognosis than FBC .

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LINK – http://www.ejinme.com/article/S0953-6205(15)00421-5/abstract